Duration 6:38

Vilsmeier Reaction

22 973 watched
0
663
Published 17 Aug 2021

What's a formylation? The introduction of a formyl group, of course. This refers to a way to make aldehydes. The Vilsmeier reaction is one such method, developed in 1927. Let's get a look at this reaction, its mechanism, and the Vilsmeier reagent itself, which continues to have new, exciting applications in synthetic chemistry. Watch the whole Organic Chemistry playlist: http://bit.ly/ProfDaveOrgChem General Chemistry Tutorials: http://bit.ly/ProfDaveGenChem Biochemistry Tutorials: http://bit.ly/ProfDaveBiochem Biology Tutorials: http://bit.ly/ProfDaveBio Classical Physics Tutorials: http://bit.ly/ProfDavePhysics1 Modern Physics Tutorials: http://bit.ly/ProfDavePhysics2 Mathematics Tutorials: http://bit.ly/ProfDaveMath EMAIL► ProfessorDaveExplains@gmail.com PATREON► http://patreon.com/ProfessorDaveExplains Check out "Is This Wi-Fi Organic?", my book on disarming pseudoscience! Amazon: https://amzn.to/2HtNpVH Bookshop: https://bit.ly/39cKADM Barnes and Noble: https://bit.ly/3pUjmrn Book Depository: http://bit.ly/3aOVDlT

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Comments - 49
  • @
    @coalyboi79393 years ago Honestly man, you've educated me so much and for FREE. I dont know how to thank you. You've explained so many questions I had in my head in a simple and eloquent way. 22
  • @
    @blackflag_N13 years ago The good ol' Vilsmeier rxn! This makes me remember my Chemistry Graduate Course in 2000! 7
  • @
    @wleizero3 years ago Whao, you forced me to learn new words and concepts :-) I accidentally heard it at 1.75x speed the first time, and it felt like drinking from a fire hydrant. Great educational content!!! 5
  • @
    @lori89283 years ago A brand new subscriber here, Prof. Dave!!! I am the mother of someone you talk to, frequently. Dustin Knight, Meteorologist @ WKU. He introduced me to your channel tonight and I am living for the content I've watched thus far! Happy to be here! ... 1
  • @
    @vm35523 years ago Thank you dear Professor
    You helped me with your huge explication
  • @
    @LordBrainzlast month I saw that you can combine this reaction with the Grignard reaction to make straight benzaldehyde, does it work?
  • @
    @kcull43 years ago I challenge anyone to pack more knowledge into a 6-minute video clip. Outstanding.
  • @
    @aonodensetsu3 years ago why am i watching this since i know nothing of organic chemistry? 4
  • @
    @adityachudasama10846 months ago SO2Cl2 can also be used... 1
  • @
    @symonbailey3 years ago Dave great channel. When a flat earther tells me that water always finds its level but then moves on to give sea level as the example. How can i respond or demonstrate the water conforming to the earth. If i test on a local or small scale it will always appear level so at what point would a body of water start deviate from being perceptually flat. A good answer to this would stop a lot if nonsense by flat earthers but as a non scientist am struggling. Keep up the good work! ...
  • @
    @gamerbadshah4363 years ago Profesa.. pliez make van on gram ikvivalent(gram equivalent)
  • @
    @rishab77463 years ago can someone tell is this in jee advanced syllabus 1
  • @
    @bracethevoid3 years ago You’re the guy who I had to watch in middle school because my teacher forced me
  • @
    @mastersonogashira17963 years ago Found the channel with debunking video, then I saw the ppt that gave me nightmare during undergrad >_<
  • @
    @Amm68x3 years ago HE SOUNDS SO MUCH LIKE SOMEONE BUT I CANT PUT MY FINGER ON IT
    His voice is like a mix of fundy and ranboo I think
  • @
    @JespMusic11 months ago Insightful, but I think you mean alpha carbon, not beta carbon
  • @
    @qwaeszrdxtfcgvbqwaeszrdxtf57332 years ago Cant we just isolate vilsmeler reagent as a salt instead of producing it in every reaction.
  • @
    @nojusvaiciulis25543 years ago Can you make a video of trying to prove that the earth is flat just for jokes
  • @
    @grandpretredesalpagas46653 years ago We know all that and yet we cannot make a SO6 molecules...
    (SO6 can be read saucisse in french which means sausage)
    1
  • @
    @KILLRXNOEVIRUS3 years ago Since when did penguinz0 do science? (jk) 5
  • @
    @coalyboi79393 years ago Honestly man, you've educated me so much and for FREE. I dont know how to thank you. You've explained so many questions I had in my head in a simple and eloquent way. 22
  • @
    @blackflag_N13 years ago The good ol' Vilsmeier rxn! This makes me remember my Chemistry Graduate Course in 2000! 7
  • @
    @wleizero3 years ago Whao, you forced me to learn new words and concepts :-) I accidentally heard it at 1.75x speed the first time, and it felt like drinking from a fire hydrant. Great educational content!!! 5
  • @
    @lori89283 years ago A brand new subscriber here, Prof. Dave!!! I am the mother of someone you talk to, frequently. Dustin Knight, Meteorologist @ WKU. He introduced me to your channel tonight and I am living for the content I've watched thus far! Happy to be here! ... 1
  • @
    @vm35523 years ago Thank you dear Professor
    You helped me with your huge explication
  • @
    @LordBrainzlast month I saw that you can combine this reaction with the Grignard reaction to make straight benzaldehyde, does it work?
  • @
    @kcull43 years ago I challenge anyone to pack more knowledge into a 6-minute video clip. Outstanding.
  • @
    @aonodensetsu3 years ago why am i watching this since i know nothing of organic chemistry? 4
  • @
    @adityachudasama10846 months ago SO2Cl2 can also be used... 1
  • @
    @symonbailey3 years ago Dave great channel. When a flat earther tells me that water always finds its level but then moves on to give sea level as the example. How can i respond or demonstrate the water conforming to the earth. If i test on a local or small scale it will always appear level so at what point would a body of water start deviate from being perceptually flat. A good answer to this would stop a lot if nonsense by flat earthers but as a non scientist am struggling. Keep up the good work! ...
  • @
    @gamerbadshah4363 years ago Profesa.. pliez make van on gram ikvivalent(gram equivalent)
  • @
    @rishab77463 years ago can someone tell is this in jee advanced syllabus 1
  • @
    @bracethevoid3 years ago You’re the guy who I had to watch in middle school because my teacher forced me
  • @
    @mastersonogashira17963 years ago Found the channel with debunking video, then I saw the ppt that gave me nightmare during undergrad >_<
  • @
    @Amm68x3 years ago HE SOUNDS SO MUCH LIKE SOMEONE BUT I CANT PUT MY FINGER ON IT
    His voice is like a mix of fundy and ranboo I think
  • @
    @JespMusic11 months ago Insightful, but I think you mean alpha carbon, not beta carbon
  • @
    @qwaeszrdxtfcgvbqwaeszrdxtf57332 years ago Cant we just isolate vilsmeler reagent as a salt instead of producing it in every reaction.
  • @
    @nojusvaiciulis25543 years ago Can you make a video of trying to prove that the earth is flat just for jokes
  • @
    @grandpretredesalpagas46653 years ago We know all that and yet we cannot make a SO6 molecules...
    (SO6 can be read saucisse in french which means sausage)
    1
  • @
    @KILLRXNOEVIRUS3 years ago Since when did penguinz0 do science? (jk) 5